Within the Start-up Tab, select and disable programs that you do not wish to auto-load when Windows starts.Right-click on a blank area of your taskbar and open Task Manager.To Add or Delete Startup Items for Only a 'Specific User'. How To Stop Programs Starting Automatically 1 Open File Explorer, and do step 2 or step 3 below for what you would like to do. This is usually in the form of a tickbox within Settings or Preferences within the software itself. Some software packages have the ability to auto-run when Windows starts. This can be useful to auto-start a music program if you have background music, or if you use the computer to display video promotional content, simply add a shortcut to the video file or music playlist. This can be useful to autorun if the system loses power when unattended. If you have a booking or appointment software package that you want to autostart when the system is launched, or if you use your PC to monitor CCTV. This can be useful if your system must be access remotely via remote desktop. Mostly for professional use such as work or business. However there are many scenarios in which you may want to auto-run particular files or programs. Normally we focus on removing programs from auto-starting.